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Antibodies

Anti-IFNAR-1 [64G12]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB02215-10-0-BT-1MG
About this Product
SKU:
AB02215-10-0-BT
Additional Names:
IFNAR1; IFN-R-1; Interferon alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1
Application:
Block/Inhibit/Neutralise, Confocal Microscopy, ELISA, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Microscopy, Western Blot
Buffer:
PBS
translate.label.attr.clone:
64G12
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Human
Immunogen:
The original antibody was generated by immunizing mice with recombinant soluble interferon (r sIFN-R) expressed and purified from E.coli or from a culture supernatant of Cos7 cells.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds the extracellular domain of the human type I-interferon receptor (IFN-R) and has neutralizing capacity against the biological properties of the human type I-IFN. The epitope to which the antibody binds was found to include the peptide: CNFSSLKLNVYE. This peptide is present in subdomain 1 of the extracellular portion of IFNAR1.
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies