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Antibodies

Anti-Tim-1 [RMT1-10]

Product Sizes
200 ug
Was £463.00 £440.00
AB02187-23-0-200UG
About this Product
SKU:
AB02187-23-0
Additional Names:
CD365; HAVcr-1; HAVCR1; Hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; KIM-1; T cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin mucin receptor 1; TIM-1; TIM1; TIMD-1
Application:
Block/Inhibit/Neutralise, ELISA, Flow Cytometry, Immunofluorescence
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
RMT1-10
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Rabbit
Immunogen:
The original rat IgG2a version of this antibody was raised by immunizing SD rats with full-length Tim-1-Ig that contained both IgV and mucin domains of Tim-1. Lymph node cells were then fused with P3U1 myeloma cells and cloned creating hybridomas.
Isotype:
IgG
Purification:
Purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for murine TIM-1, a member of the T cell immunoglobulin domain, mucin-like domain (TIM) gene family. IgV domain of Tim-1 was proposed as the epitope of RMT1-10 (Xiao et al., 2007; pmid: 17606630). RMT1-10 did not corss-react with Tim-4-Ig fusion proteins. 3B3 - an anti-Tim-1 antibody with opposite, T-cell activatory effects blocked binding of RMT1-10 suggesting the same o
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies