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Antibodies

Anti-Pan-Shank Pan [N23B/49]

Product Sizes
200 ug
Was £463.00 £440.00
AB02158-10-3-200UG
About this Product
SKU:
AB02158-10-3
Additional Names:
N23B/49R; SH3 and multiple ankyrin repeat domains protein 2; Cortactin-binding protein 1; CortBP1; GKAP/SAPAP-interacting protein; Proline-rich synapse-associated protein 1; ProSAP1; SPANK-3
Application:
Immunocytochemistry, Immunofluorescence, Western Blot
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
N23B/49
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 84-309 (SH3/PDZ domains) of rat Shank2.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human, Mouse, Rat, Wide/Non-species Specific
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for shank1, shank2 and shank3. Shank2 seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies