Anti-Pan-Shank Pan [N23B/49]
Product Sizes
1 mg
AB02158-10-3-BT-1MG
About this Product
- SKU:
- AB02158-10-3-BT
- Additional Names:
- N23B/49R; SH3 and multiple ankyrin repeat domains protein 2; Cortactin-binding protein 1; CortBP1; GKAP/SAPAP-interacting protein; Proline-rich synapse-associated protein 1; ProSAP1; SPANK-3
- Application:
- Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- N23B/49
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 84-309 (SH3/PDZ domains) of rat Shank2.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Mouse, Rat, Wide/Non-species Specific
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for shank1, shank2 and shank3. Shank2 seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02158-10.3-BT
