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Antibodies

Anti-IL-6 [68F2]

Product Sizes
200 ug
AB02026-10-3-200UG
About this Product
SKU:
AB02026-10-3
Additional Names:
IL6; IFNB2; BSF-2; CDF; Interleukin-6; IL-6; B-cell stimulatory factor 2; CTL differentiation factor; Hybridoma growth factor; Interferon beta-2; IFN-beta-2
Application:
ELISA
Buffer:
PBS with 0.02% Proclin 300.
Clone:
68F2
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Fab format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original antibody was generated by immunizations of Llama glama with recombinant IL-6 followed by construction of phage display library, selection, screeing and purification.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody recognizes and binds interleukin-6 near the binding site I near the N-terminal part of A Alpha-helix 1 and the C-terminal part of A Alpha-helix 4 of the four-helix bundle, as well as the long loop between A Alpha-helices 1 and 2. This binding interface of 68F2 to a major extent overlaps with site I recognized by IL-6R.
Storage Conditions:
2-8[o]C Aliquot.
Type:
Antibody: Recombinant Antibodies