Anti-H4 K8Ac; K12Ac; K16Ac [KM-2]
Product Sizes
1 mg
AB01681-10-3-BT-1MG
About this Product
- SKU:
- AB01681-10-3-BT
- Additional Names:
- histone 4; nucleosome; H4K8Ac; H4K12Ac; H4K16Ac; acetyl-Histone H4; Histone H4 acetylated at lysine; KM2
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- KM-2
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- KM-2 antibody was derived from an MRL/lpr lupus mouse.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- KM-2 antibody recognizes the N-terminal peptides 1-20 of histone H2A and 1-29 of histone H4 which have a large sequence homology (van Bruggen et al., 1997; pmid: 9027774). Histone H4 acetylation on lysines 8, 12 and 16 significantly increases the antibody's binding while the acetylation at K5 decreases it (Dieker et al., 2007; pmid: 17530637).
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab01681-10.3-BT
