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Antibodies

Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]

Product Sizes
50 ug
AB01680-46-0-IST-50UG
About this Product
SKU:
AB01680-46-0-IST
Additional Names:
Spike protein; COVID19; COVID 19; S protein; SARS-CoV S protein; S glycoprotein; E2; Peplomer protein; Spike protein S1; SARS Coronavirus; SARS-CoV-2; SARS CoV 2; 2019-nCoV; Ab1680.10; Ab1680.15; Ab1680.16
Application:
Block/Inhibit/Neutralise, Crystallography, ELISA, Immunofluorescence, Surface Plasmon Resonance
Buffer:
PBS with 0.02% Proclin 300
translate.label.attr.clone:
CR3022
Clonality:
Recombinant Monoclonal
Extra Details:
This is a blend of IgG1, IgG3, IgM and IgA versions of CR3022. Each antibody format is present at 0.25 mg/ml, for a total antibody concentration of 1 mg/ml.
Formulation:
PBS with 0.02% Proclin 300
Host:
Human
Immunogen:
The original monoclonal antibody was generated through an scFv library derived from a peripheral blood lymphocytes of a patient exposed to the SARS-CoV.
Isotype:
IgA, IgG1, IgG3, IgM
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds the amino acids 318-510 in the S1 domain of the SARS-CoV Spike protein as well as SARS-CoV-2 (COVID-19) Spike protein. The antibody also binds to P462L-substituted S318-510 fragments of the SARS spike protein. The binding epitope is only accessible in the "open" confromation of the spike protein (Joyce et al. 2020).
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies