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Antibodies

Anti-SARS-CoV S glycoprotein [A11]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB01669-10-3-BT-1MG
About this Product
SKU:
AB01669-10-3-BT
Additional Names:
Spike protein; S protein; SARS-CoV S protein; S glycoprotein; E2; Peplomer protein; Spike protein S2
Application:
ELISA, Immunofluorescence, Western Blot
Buffer:
PBS
translate.label.attr.clone:
A11
Clonality:
Recombinant Monoclonal
Extra Details:
This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Human
Immunogen:
The original antigen was produced by subcloning the scFv gene fragment in an expression vector like pET32b, and transforming the vector into an E.coli strain BL21 and inducing expression by IPTG ( isopropyl-b-D-thiogalactopyranoside). A scFv phage antibody library was constructed in fd phage. The antibody was produced by panning against S2b, two non-immune human Ab phage display libraries and neutralizing activity was tested against pseudotyped viruses. Antigen binding antibodies were identified by phage ELISA.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Specificity:
This antibody specifically binds the epitope in the S2 domain of the spike protein in the region of Leu803-Ala828.
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies