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Antibodies

Anti-OspA [184.1]

Product Sizes
100 ug
Was £623.00 £592.00
AB01572-10-0-100UG
About this Product
SKU:
AB01572-10-0
Additional Names:
Outer surface protein A
Application:
Crystallization, ELISA, Western Blot
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
184.1
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
BALB/c mice were immunised by injection of B. burgdorferi sonicated preparations. Splenocytes were obtained from immunised mice and fused with X63-Ag8 myeloma cells to generate hybridomas.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Bacteria
Shipping Conditions:
Blue Ice
Specificity:
184.1 was shown to react specifically with a common OspA epitope shared by a homologous protein of lower molecular weight (Jiang et al, 1990). Based on N-terminal sequencing and reactivity of 184.1 against truncated versions of OspA, it was concluded that 184.1 recognises an N-terminal epitope of OspA. This was corroborated by a crystal structure of the OspA-184.1 Fab structure (Li et al, 1997), w
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies