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Antibodies

Anti-CD47 [mIAP301]

Product Sizes
50 mg
AB01569-3-3-VXF-50MG
About this Product
SKU:
AB01569-3-3-VXF
Additional Names:
IAP; Leukocyte surface antigen CD47; Integrin-associated protein; integrin associated protein; MIAP 301; MIAP-301
Application:
Block/Inhibit/Neutralise, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot
Buffer:
PBS
translate.label.attr.clone:
mIAP301
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Mouse
Immunogen:
MIAP301 was prepared by immunizing rats with intact CD47 purified from mouse placenta.
Isotype:
IgG2b
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
MIAP301 binds specifically to the extracellular domain of CD47 (exon 2 that encodes both the predicted signal peptide clevage site and the entire Ig domain). CD47 plays a role in cell adhesion by acting as an adhesion receptor for THBS1 on platelets and in (beta-3) integrin modulation. Functions as a SIRPA receptor - binding prevents maturation of immature dendritic cells and inhibits cytokine pro
Storage Conditions:
Please refer to datasheet
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies