Anti-C3b-iC3b [7C12]

Product Sizes

1 mg

AB01554-10-0-BT-1MG

About this Product

SKU:: AB01554-10-0-BT
Additional Names:: Complement C3; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
Application:: ELISA, Flow Cytometry, Immunofluorescence, Western Blot
Buffer:: PBS
translate.label.attr.clone:: 7C12
Clonality:: Recombinant Monoclonal
Extra Details:: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Formulation:: PBS only.
Host:: Human
Immunogen:: The mouse version of this antibody was raised by immunizing a mouse with human C3b and iC3b bound to a carbohydrate matrix via the alternative pathway of complement activation.
Isotype:: IgG1
Purification:: Purified
Reactivities:: Human
Shipping Conditions:: Blue Ice
Specificity:: This antibody is specific for human C3b. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
Storage Conditions:: 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:: Absolute Antibody
Type:: Antibody: Recombinant Antibodies

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