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Antibodies

Anti-SIRP alpha [SAF10.1]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB01531-8-1-BT-1MG
About this Product
SKU:
AB01531-8-1-BT
Additional Names:
Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Macrophage fusion receptor; MyD-1 antigen; Signal-regulatory protein alpha-1; Sirp-alpha-1; Signal-regulatory protein alpha-2; Sirp-alpha-2; Signal-regulatory protein alpha-3; Sirp-alpha-3; p84; CD172a
Application:
Cell-based/Functional Assay, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot
Buffer:
PBS
translate.label.attr.clone:
SAF10.1
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Rat
Immunogen:
This antibody was raised by immunisisng BALB/c mice with an eukaryotically expressed SIRPA Alpha-Fc fusion protein consisting of the extracellular domain and emulsified with complete Freund's adjuvant and followed by two subsequent boosts of SIRPA Alpha-Fc fusion protein emulsified with IFA (Lee et al., 2007).
Isotype:
IgG2b
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody recognises an epitope in the membrane most distal domain (D1) of SIRP alpha. It crossreacts with other SIRPs.
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies