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Antibodies

Anti-GABAR [1F4]

Product Sizes
200 ug
Was £463.00 £440.00
AB01411-10-3-200UG
About this Product
SKU:
AB01411-10-3
Additional Names:
Gamma-aminobutyric acid receptor A; Gamma-aminobutyric acid receptor; Gamma-aminobutyric acid receptor subunit alpha-1; Gamma-aminobutyric acid receptor subunit beta-2; Gamma-aminobutyric acid receptor subunit gamma-2; GABA(A); GABA-A receptor; A Alpha1B Beta2G Gamma2 GABA-A receptor
Application:
Crystallography, FSEC
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
1F4
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
This antibody was raised against A Alpha1B Beta2G Gamma2 GABA-A receptor.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody recognises A Alpha1B Beta2G Gamma2 GABA-A receptor which is found in up to 50% of the synapses in the brain. It's ligand, GABA is a major inhibitory transmitter in the nervous system, binds to this receptor and opens a channel permeable to chloride. Disfunctions of GABAR are found in anxiety, neurodevelopmental disorderds and epilepsy.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies