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Antibodies

Anti-IL2R gamma C [3E12]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB01370-2-0-BT-1MG
About this Product
SKU:
AB01370-2-0-BT
Additional Names:
CD132; IL2R gamma C; common gamma chain; common y chain; gamma chain; IL-2 receptor gamma chain; Interleukin-2 receptor subunit gamma; Cytokine receptor common subunit gamma; Il2rg; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; gammaC; p64
Application:
Block/Inhibit/Neutralise, Flow Cytometry, Immunoprecipitation
Buffer:
PBS
translate.label.attr.clone:
3E12
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Mouse
Immunogen:
This antibody was raised by immunising Lewis rats with transfected rat myeloma cell line YB2/0, expressing murine cytoplasmic-tailless IL-2R common gamma-chain (YB2/0-myt).
Isotype:
IgG2a
Purification:
Purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
This conformation-dependent antibody binds to the murine common gamma-chain, shared by the IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21 receptor complexes. It recognises an epitope located in a membrane-proximal portion of the common gamma-chain, near Arg-197 of domain 2. This antibody does not cross-react with COS7 cells transfected with rat common gamma-chain cDNA (Olosz et al, 2002).
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies