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Antibodies

Anti-EME1 [7h2/1]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB01301-23-0-BT-1MG
About this Product
SKU:
AB01301-23-0-BT
Additional Names:
Essential meiotic endonuclease 1; Crossover junction endonuclease EME1; MMS4 homolog; hMMS4; EC 3.1.22; EC 3.1.22.; essential meiotic endonuclease 1 homolog 1 (S. pombe); essential meiotic endonuclease 1 homolog 2; FLJ31364; homolog of yeast EME1 endonuclease; MMS4L; MMS4; SLX2 structure-specific endonuclease subunit homolog A; SLX2A; MTA31
Application:
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS
translate.label.attr.clone:
7h2/1
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Rabbit
Immunogen:
The antibody was raised against His-tagged recombinant Eme1 of human origin.
Isotype:
IgG
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody recognises human EME1. EME1 together with MUS81 create a DNA endonuclease which binds preferentially to branched DNA structures such as Holliday junctions and replication forks. It's engaged in processing of stalled or collapsed replication forks in mitosis.
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies