Anti-IL-21R [ATR-107]
Product Sizes
1 mg
AB01293-10-0-BT-1MG
About this Product
- SKU:
- AB01293-10-0-BT
- Additional Names:
- CD360; Ab01; Ab-01; ATR107; IL21R; Interleukin-21 receptor; IL-21 receptor; NILR; Novel interleukin receptor; Q9JHX3
- Application:
- Block/Inhibit/Neutralise
- Buffer:
- PBS
- translate.label.attr.clone:
- ATR-107
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- This antibody was isolated through phage display. The scFv parental clone (18A5), which binds human IL-21R, was isolated from the CS human scFv library, using BaF3 cells expressing human IL-21R and biotinylated IL-21R-Fc fusion protein. Four phage display libraries were constructed based on 18A5, and variants with increased affinity for both human and murine IL-21R were identified, including ATR-107.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Mouse, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody recognises both human and murine IL-21R extracellular domains, as both were used as targets during alternating rounds of phage display library panning. This antibody also binds to rat and cynomolgus monkey IL-21R, but does not cross-react with human IL-4RA Alpha or IL-2RB Beta.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab01293-10.0-BT
