Anti-alpha-5 TMD [Nb25]
Product Sizes
200 ug
AB01199-23-0-200UG
About this Product
- SKU:
- AB01199-23-0
- Additional Names:
- GABRA5; Gamma-aminobutyric acid receptor subunit alpha-5; GABA(A) receptor subunit alpha-5
- Application:
- Crystallization
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- Nb25
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rabbit antibody was made using the variable domain sequences of the original VHH format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Rabbit
- Immunogen:
- A llama was immunized six times with recombinant 1D4-tagged human a1b3 GABAAR pentamer. Nanobodies were selected by phage display, and the clones were then screened for binding to the receptor. From these clones Nb25 was selected.
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Binds to the transmembrane domain of the alpha-5 GABAA receptor. To see the exact epitope see the crystal structure (Miller et al, 2017). Nb25 straddles the neurotransmitter-binding site between adjacent subunits.
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab01199-23.0
