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Antibodies

Anti-DNA-RNA hybrid [S9.6]

Product Sizes
25 ug
Was £214.00 £203.00
AB01137-1-6-T-25UG
About this Product
SKU:
AB01137-1-6-T
Additional Names:
DNA:RNA Duplex; DNA-RNA Duplex; DNA/RNA Duplex; DNA-RNA Hybrid; DNA/RNA Hybrid; DNA:RNA Hybrid; RNA-DNA Duplex; RNA/DNA Duplex; RNA:DNA Duplex; RNA-DNA Hybrid; RNA/DNA Hybrid; RNA:DNA Hybrid
Application:
ChIP, Dot Blot, FISH, Gel Shift/EMSA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Proximity Ligation Assay, Surface Plasmon Resonance
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
S9.6
Clonality:
Recombinant Monoclonal
Extra Details:
This reformatted mouse Fab was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Mouse
Immunogen:
This antibody was generated in BALB/c mouse against S9.6 F PhiX174 bacteriophage-derived synthetic DNA/RNA antigen according to the protocol by Boguslawski et al. (J. Immunol Methods. 1986).
Purification:
Purified
Reactivities:
Wide/Non-species Specific
Shipping Conditions:
Blue Ice
Specificity:
This antibody demonstrates high specificity and affinity for DNA/RNA hybrids and other A-form nucleic acid hybrids, making it an effective tool for detecting R-loops. It does not cross-react with single-stranded DNA, double-stranded DNA, RNA, or ribosomal RNA. In the original study by Boguslawski et al. (1986), the antibody was shown to bind DNA-RNA heteropolymers and poly(I)-poly(dC) with equal a
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies