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Antibodies

Anti-CD11b [M1/70]

Product Sizes
1 mg
£1962.00
AB01114-8-4-BT-1MG
About this Product
SKU:
AB01114-8-4-BT
Additional Names:
Mac-1 alpha; CD11 antigen-like family member B; CD11B (p170); cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component receptor 3 alpha-a; complement receptor type 3; CR-3 alpha chain; integrin alpha-M; leukocyte adhesion receptor MO1; macrophage antigen alpha
Application:
Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS
translate.label.attr.clone:
M1/70
Clonality:
Recombinant Monoclonal
Formulation:
PBS only.
Host:
Rat
Immunogen:
This antibody was raised by immunising DA (dark agouti) and Albino Oxford (AO) strain inbred rats with nylon wool-purified B10 mouse spleen cells according to the protocol by Springer et al. (Eur J Immunol. 1978).
Isotype:
IgG2b
Purification:
Purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
This antibody reacts with mouse CD11b, the 165-170 kDa integrin alphaM. CD11b non-covalently associates with CD18 to form alphaMbeta2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. The Mac-1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, and blood monocytes. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thy
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies