Anti-TIM-2 [RMT2-14]
Product Sizes
5 mg
AB01092-2-3-VXM-5MG
About this Product
- SKU:
- AB01092-2-3-VXM
- Additional Names:
- TIMD2; T Cell Immunoglobulin Mucin-2; T Cell immunoglobulin and mucin domain protein 2; TIM3
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, Flow Cytometry, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- RMT2-14
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- This antibody was raised by immunising Sprague Dawley rats with TIM-2-Ig consisting of the extracellular domain (aa 1-230 of mouse TIM-2) and the Fc portion of mouse IgG2a, emulsified in complete Freund's adjuvant and then fusing lymph node cells from the immunized rats with P3U1 myeloma cells.
- Isotype:
- IgG2a
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for murine TIM-2, a transmembrane protein that is expressed on activated T cells and preferentially on differentiated Th2 cells. A blockade of TIM-2/TIM-2 ligand interaction results in T cell hyperproliferation and Th2 cytokine production. TIM-2 plays a critical role in the development of atopic disease and other Th2-biased immune responses.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab01092-2.3-VXM
