Anti-CCRL2 [BZ2E3]
Product Sizes
500 ug
£2625.00
AB01034-1-32-BT-500UG
About this Product
- SKU:
- AB01034-1-32-BT
- Additional Names:
- CCR11; C-C chemokine receptor-like 2;Chemokine receptor CCR11; CKRX; CRAM-A; CRAM-B; G-protein coupled beta chemokine receptor; L-CCR; Lipopolysaccharide-inducible C-C chemokine receptor
- Application:
- Cell-based/Functional Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- BZ2E3
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- This antibody was raised by immunising Wistar Furth rats with the mCCRL2 peptide/KLH conjugate. The immunizing amino-terminal mCCRL2 peptide with the sequence NH2-MDNYTVAPDDEYDVLILDDYLDNSC-COOH, corresponding to residues 1-24 of mCCRL2, with a nonnative carboxyl-terminal cysteine to facilitate conjugation to keyhole limpet hemocyanin (KLH).
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for murine CCRL2 (formerly known as L-CCR), which is expressed on mast cells, activated macrophages, and endothelial cells. This receptor binds the leukocyte chemoattractant chemerin without triggering classical GPCR signaling, providing a specific mechanism for local enrichment of chemerin at inflammatory sites. CCRL2 presents active chemerin to leukocytes expressing the
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab01034-1.32-BT
