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Antibodies

Anti-CD80 [RM80]

Product Sizes
50 mg
Was £6251.00 £5938.00
AB01028-3-3-VXF-50MG
About this Product
SKU:
AB01028-3-3-VXF
Additional Names:
B7-1; Activation B7-1 antigen; B7; B7 protein; B7-1 protein; B7.1; Cd28l; CD28LG; CD28LG1; LAB7; Ly-53; Ly53; MIC17; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1
Application:
Block/Inhibit/Neutralise, Cell-based/Functional Assay, Flow Cytometry, Immunohistochemistry, Western Blot
Buffer:
PBS
translate.label.attr.clone:
RM80
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Mouse
Immunogen:
This antibody was raised by immunising Sprague Dawley rats with a mouse B cell line, BCL1 and fusing immune splenocytes with P3U1 myeloma cells.
Isotype:
IgG2b
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for murine CD80, a ~55 kDa member of the Ig superfamily. CD80 is expressed by macrophages, dendritic cells, activated B cells, and activated T cells. CD80 has high affinity for binding to two T cell surface antigens, CD28 and CD152 (CTLA-4). The interaction of CD28 and CD152 with CD80 is crucial in T-B cell communication leading to the activation of T and B cells, respect
Storage Conditions:
Please refer to datasheet
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies