Anti-JAML [HL4E10 ]
Product Sizes
200 ug
AB00949-22-0-200UG
About this Product
- SKU:
- AB00949-22-0
- Additional Names:
- MICA1; Junctional adhesion molecule-like; Adhesion molecule interacting with CXADR antigen 1; Dendritic cell-specific protein CREA7-1
- Application:
- Crystallization, FACS, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Surface Plasmon Resonance
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- HL4E10
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Hamster
- Immunogen:
- An Armenian hamster was immunised with the 7-17 dendritic epidermal T cell line. Splenocytes were obtained from immunised hamsters and fused with the X63Ag8.653 myeloma cell line to generate a hybridoma.
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- HL4E10 was found to be specific for JAML, as this protein was identified as the ligand for the mAb from immunoprecipitation (Witherden et al, 2010). Biochemical binding studies showed that HL4E10 bound the JAML D2 Ig domain, which was corroborated with a recent crystal structure of the JAML ECD and a HL4E10 Fab fragment (Verdino et al, 2011). HL4E10 has an affinity for JAML of 8 nM, characterised
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00949-22.0
