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Antibodies

Anti-Envelope protein DIII [2D73]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB00948-1-1-BT-1MG
About this Product
SKU:
AB00948-1-1-BT
Additional Names:
DENV E DIII; Dengue virus envelope protein domain III; DENV envelope protein domain III; 2D-73
Application:
Crystallization, ELISA
Buffer:
PBS
translate.label.attr.clone:
2D73
Clonality:
Recombinant Monoclonal
Formulation:
PBS only.
Host:
Mouse
Immunogen:
BALB/c mice were immunised with recombinantly-produced envelope protein domain III (EDIII) from DENV-3. Splenocytes were obtained from immunised mice and fused with the NS-1 myeloma cell line to generate hybridomas.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Specificity:
2D73 reacts with residues 309-319 (DKEMAETQHGT) within domain III of the DENV envelope protein, shown crystallographically (Li et al, unpublished). Although raised against DENV-3 EDIII, 2D72 cross-reacts with EDIII from all four DENV serotypes. 2D73 does not react with other DENV-related flaviviruses, such as WNV, YFV and JEV.
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies