Anti-Envelope protein (soluble) [Z23]
Product Sizes
1 mg
AB00941-10-0-BT-1MG
About this Product
- SKU:
- AB00941-10-0-BT
- Additional Names:
- ZIKV sE; Zika virus soluble envelope protein; Zika virus envelope protein; ZIKV soluble envelope protein; ZIKV envelope protein; Zika virus sE protein; ZIKV sE protein; ZIKV sE; Z-23
- Application:
- Block/Inhibit/Neutralise, ELISA, Flow Cytometry, Surface Plasmon Resonance
- Buffer:
- PBS
- translate.label.attr.clone:
- Z23
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- Anti-ZIKV mAbs were obtained from the sera and peripheral blood mononuclear cells of a ZIKV-infected patient.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Virus
- Shipping Conditions:
- Blue Ice
- Specificity:
- Z23 binds to the ZIKV soluble envelope (sE) protein, shown using ELISAs, SPR and kinetic competition assays (Wang et al, 2016). This mAb is highly specific for ZIKV, and was shown to exhibit no neutralisation activity against DENV-1 to DENV-4 virions, which are highly related to ZIKV. Z23 was shown to bind domain III of sE by cryo-electron microscopy. ZIKV has recently become a major global health
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00941-10.0-BT
