Anti-Envelope protein (soluble) [Z3L1]
Product Sizes
1 mg
AB00940-13-12-BT-1MG
About this Product
- SKU:
- AB00940-13-12-BT
- Additional Names:
- ZIKV sE; Zika virus soluble envelope protein; Zika virus envelope protein; ZIKV soluble envelope protein; ZIKV envelope protein; Zika virus sE protein; ZIKV sE protein; Z3-L1
- Application:
- Block/Inhibit/Neutralise, Crystallization, ELISA, Flow Cytometry, Surface Plasmon Resonance
- Buffer:
- PBS
- translate.label.attr.clone:
- Z3L1
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- Anti-ZIKV mAbs were obtained from the sera and peripheral blood mononuclear cells of a ZIKV-infected patient.
- Isotype:
- IgG4
- Purification:
- Purified
- Reactivities:
- Virus
- Shipping Conditions:
- Blue Ice
- Specificity:
- Z3L1 binds to the ZIKV soluble envelope (sE) protein, shown using SPR, kinetic competition assays and crystallography (Wang et al, 2016). This mAb is highly specific for ZIKV, and was shown to exhibit no neutralisation activity against DENV-1 to DENV-4 virions, which are highly related to ZIKV. It was shown crystallographically that the Z3L1 Fab region binds to domain I and domain II of sE. ZIKV h
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00940-13.12-BT
