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Antibodies

Anti-Envelope protein (soluble) [Z3L1]

Product Sizes
200 ug
Was £463.00 £440.00
AB00940-10-0-200UG
About this Product
SKU:
AB00940-10-0
Additional Names:
ZIKV sE; Zika virus soluble envelope protein; Zika virus envelope protein; ZIKV soluble envelope protein; ZIKV envelope protein; Zika virus sE protein; ZIKV sE protein; Z3-L1
Application:
Block/Inhibit/Neutralise, Crystallization, ELISA, Flow Cytometry, Surface Plasmon Resonance
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
Z3L1
Clonality:
Recombinant Monoclonal
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
Anti-ZIKV mAbs were obtained from the sera and peripheral blood mononuclear cells of a ZIKV-infected patient.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Specificity:
Z3L1 binds to the ZIKV soluble envelope (sE) protein, shown using SPR, kinetic competition assays and crystallography (Wang et al, 2016). This mAb is highly specific for ZIKV, and was shown to exhibit no neutralisation activity against DENV-1 to DENV-4 virions, which are highly related to ZIKV. It was shown crystallographically that the Z3L1 Fab region binds to domain I and domain II of sE. ZIKV h
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies