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Antibodies

Anti-JMJD6 [APSR-14.4]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB00928-10-0-BT-1MG
About this Product
SKU:
AB00928-10-0-BT
Additional Names:
HisArgDeMe; Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Histone arginine demethylase JMJD6; Jumonji domain-containing protein 6; JmjC domain-containing protein 6; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine recep
Application:
Crystallization, Immunofluorescence, Immunoprecipitation, Western Blot
Buffer:
PBS
translate.label.attr.clone:
APSR-14.4
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Hamster IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Human
Immunogen:
APSR-14.4 was produced by immunising Armenian hamsters using human His-tagged JMJD6.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
APSR-14.4 was shown crystallographically to bind the C-terminal helix-turn-helix domain of JMJD6 (Hong et al, 2010). JMJD6 was initially identified as a phosphatidylserine receptor, but is now known to be a multifunctional histone modifier which may also be implied in RNA splicing. JMJD6 expression levels have more recently been associated with poor outcomes in breast cancer tumours (Lee et al, 20
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies