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Antibodies

Anti-CD29 [12G10]

Product Sizes
200 ug
Was £463.00 £440.00
AB00849-13-12-200UG
About this Product
SKU:
AB00849-13-12
Additional Names:
Integrin beta-1; Integrin B Beta1 chain; Integrin B Beta1; VLA-B Beta chain; Glycoprotein Iia; GPIIA; Fibronectin receptor subunit beta; ITGB1; VLA-4 subunit beta; FNRB; MDF2; MSK12
Application:
ELISA, Enhancement, Flow Cytometry, Immunohistochemistry, Western Blot
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
12G10
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
This antibody was raised by immunising BALB/C mice with purified B Beta1 integrins from HT-1080 fibrosarcoma cells
Isotype:
IgG4
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody recognises a ligand-induced binding site on the B BetaA domain of B Beta1 integrin, and thus reacts preferentially with A Alpha5B Beta1 integrins in the ligand-activated state. Binding of this antibody alters the position of the A Alpha1 helix of B Beta1 integrin, and results in further integrin activation.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies