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Antibodies

Anti-deltaEGFR [DH8.3]

Product Sizes
200 ug
Was £463.00 £440.00
AB00822-13-12-200UG
About this Product
SKU:
AB00822-13-12
Additional Names:
D DeltaEGFR; Epidermal growth factor receptor; EC:2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; EGFR; ERBB; ERBB1; HER1
Application:
ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
DH8.3
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
This antibody was raised by immunising BALB/c mice with a synthetic peptide, known as 79E (LEEKKGNYVVTDHC), corresponding to the junctional sequence of the D Delta2-7 EGFR deletion mutation.
Isotype:
IgG4
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for D DeltaEGFR (EGFR type III), a truncated form of the epidermal growth factor receptor that is commonly associated with cancer cells, especially glioblastoma cells. D DeltaEGFR lacks exons 2-7 of the external domain. This antibody does not cross-react with full-length EGFR.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies