Anti-deltaEGFR [DH8.3]
Product Sizes
1 mg
AB00822-10-3-BT-1MG
About this Product
- SKU:
- AB00822-10-3-BT
- Additional Names:
- D DeltaEGFR; Epidermal growth factor receptor; EC:2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; EGFR; ERBB; ERBB1; HER1
- Application:
- ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- DH8.3
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- This antibody was raised by immunising BALB/c mice with a synthetic peptide, known as 79E (LEEKKGNYVVTDHC), corresponding to the junctional sequence of the D Delta2-7 EGFR deletion mutation.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for D DeltaEGFR (EGFR type III), a truncated form of the epidermal growth factor receptor that is commonly associated with cancer cells, especially glioblastoma cells. D DeltaEGFR lacks exons 2-7 of the external domain. This antibody does not cross-react with full-length EGFR.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00822-10.3-BT
