Anti-BCR-ABL [7c6]
Product Sizes
1 mg
AB00817-10-0-BT-1MG
About this Product
- SKU:
- AB00817-10-0-BT
- Additional Names:
- BCR/ABL; Breakpoint cluster region protein-tyrosine protein kinase ABL1 fusion protein
- Application:
- Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 7c6
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- Murine antibodies were produced by immunising BALB/c mice with residues 686-696 (SSINEEITPRRQS) of human BCR fused to thyroglobulin. Hybridomas were generated by fusion of immunised cells with the myeloma cell line P3X63Ag8 via established methods.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for the SSINEEITPRRQS epitope of BCR (residues 686-696), and as such is able to recognise full-length BCR and the p210 form of the BCR-ABL fusion protein. p210 BCR-ABL is a cytogenetic marker of chronic myelogenous leukaemia, resulting from gross chromosomal translocation resulting in the 'Philadelphia chromosome'. The fusion protein is a constitutively active tyrosine ki
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00817-10.0-BT
