Anti-HIV-1/HIV-2 protease [1696]
Product Sizes
500 ug
AB00806-47-0-BT-500UG
About this Product
- SKU:
- AB00806-47-0-BT
- Additional Names:
- HIV-1 PR; HIV-2 PR; HIV-1 protease; HIV-2 protease; HIV1 PR; HIV2 PR; HIV1 protease; HIV2 protease
- Application:
- Block/Inhibit/Neutralise, ELISA, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 1696
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This reformatted human antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- 1696 was prepared by generating a hybridoma cell line, fusing myeloma cells with splenocytes derived from BALB/c mice immunized with HIV-1 PR in the presence of Freund's adjuvant.
- Isotype:
- IgA2
- Purification:
- Purified
- Reactivities:
- Virus
- Shipping Conditions:
- Blue Ice
- Specificity:
- 1696 binds to HIV-PR of both HIV-1 and HIV-2 (IgG 1696: HIV-1 PR pH5.7 ~350 uM; pH7.4 ~100 nM - HIV-2 PR pH5.7 no measurable interaction; pH7.4 ~30 nM -- Fab 1696: HIV-1 PR pH5.7 ~410 nM; pH7.4 ~130 nM - HIV-2 PR pH5.7 no measureable interaction; pH7.4 ~40 nM-- determined by ELISA). The antibody binds to the N-terminal region of the enzyme, and binding is inhibited by the peptide fragment PQITLWQ
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00806-47.0-BT
