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Antibodies

Anti-single-stranded poly(rI) RNA [Jel 103]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB00800-3-0-BT-1MG
About this Product
SKU:
AB00800-3-0-BT
Additional Names:
polyriboinosinic acid; single stranded RNA; single-stranded RNA; inosine
Application:
Immunofluorescence, Radioimmunoassay
Buffer:
PBS
translate.label.attr.clone:
Jel 103
Clonality:
Recombinant Monoclonal
Formulation:
PBS only.
Host:
Mouse
Immunogen:
Jel 103 was selected from a hybridoma cell line generated by the fusion of the MOPC 315-43 myeloma cell line with mouse spleen cells derived from C57/B1 mice which had been immunized with poly(rI)poly(dC) duplex complexed to methylated bovine serum albumin.
Isotype:
IgG2b
Purification:
Purified
Reactivities:
Wide/Non-species Specific
Shipping Conditions:
Blue Ice
Specificity:
Jel 103 is highly specific for single-stranded RNA and shows sequence specificity as it binds to poly(rI) but not to poly(dI), poly(rG) or to any other homopolymer - it does not bind randomly to calf thymus DNA. Jel 103 Fab is shown to form base stacking interactions with a Tyr residue and two salt-bridge interactions to the phosphate backbone with Lys and Arg residues.
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies