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Antibodies

Anti-desmosome/hemidesmosome [F12]

Product Sizes
200 ug
Was £463.00 £440.00
AB00797-23-0-200UG
About this Product
SKU:
AB00797-23-0
Application:
Immunoelectron Microscopy, Immunofluorescence
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
F12
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgM format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Rabbit
Immunogen:
F12 was established by fusing peripheral blood lymphocytes derived from a human vulgaris patient with a hetermyeloma cell line.
Isotype:
IgG
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
F12 recognizes an unknown polypeptide of desmosomal and hemidesmosomal plaques with a MW of 185 kDa (determined from immunoblotting using bovine tongue epithelium extract as the substrate), and by IEM (immunoelectron microscopy) it was determined that it is the intracellular part of the desmosome that is bound (Gilbert, 1997). F12 shares some immunochemical properties with autoantibodies present i
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies