Anti-Parathyroid Hormone-related Protein [23-57-137-1]
Product Sizes
200 ug
AB00795-1-1-200UG
About this Product
- SKU:
- AB00795-1-1
- Additional Names:
- PTHrP; PTH-rP; Parathyroid hormone-like protein; PLP; PTHrP[1-34]
- Application:
- Block/Inhibit/Neutralise, Crystallization
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- 23-57-137-1
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Mouse
- Immunogen:
- The anti-PTHrP antibody was prepared by immunizing mice with synthetic human bovine thyroglobulin-conjugated PTHrP (aa 1-34) and generating the hybridoma cell line #23-57-137-1
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The Antibody binds to human PTHrP (The KD ~ 0.1 nM) at a site closely overlapping with the GPCR parathyroid hormone receptor 1 binding site - the epitope is between residues 20 and 30, with some contribution from residues 15-20 (aa 14-34 are important for receptor binding and aa1-34 are important for full signal tranduction). PTHrP is known to be a causative factor of humoural hypercalcemia of mal
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00795-1.1
