Anti-Ebola GP [h-13F6]
Product Sizes
1 mg
AB00790-23-0-BT-1MG
About this Product
- SKU:
- AB00790-23-0-BT
- Additional Names:
- GP1; Envelope glycoprotein; EBOV glycoprotein; EBOV GP
- Application:
- ELISA, Immunoprecipitation, Surface Plasmon Resonance
- Buffer:
- PBS
- translate.label.attr.clone:
- h-13F6
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Rabbit
- Immunogen:
- Murine 13F6 (IgG2a) was prepared by immunizing BALB/c mice with packaged Venezuelan equine encephalitis virus replicons encoding the GP from the Mayinga isolate of Ebola virus Zaire 1976. Murine 13F6 was deimmunized (to remove T-cell epitopes from the variable region sequences) and chimerized with human IgG1 constant regions to create h13F6.
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Virus
- Shipping Conditions:
- Blue Ice
- Specificity:
- h-13F6 binds specifically to the linear epitope ATQVEQHHRRTDNDSTA (aa 401-417) on Ebola Virus Zaire GP1. Proteolytic processing of GP results in two products, GP1 and membrane-bound GP2, that covalently associate to form a monomer of the GP spike found on the surfaces of virions. GP1 is also released from infected cells in a soluble form. The Ebola virus is of the family Filoviridae and causes acu
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00790-23.0-BT
