Anti-Sag1 [4F11E12]
Product Sizes
1 mg
AB00763-10-0-BT-1MG
About this Product
- SKU:
- AB00763-10-0-BT
- Additional Names:
- P30
- Application:
- Crystallization
- Buffer:
- PBS
- translate.label.attr.clone:
- 4F11E12
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- 4F11E12 was generated by intraperitoneal infection of mice with cysts from the 76 K T. gondii strain and was selected for its ability to inhibit efficiently the recognition of SAG1 by sera from infected patients. The 4F11E12 Fab fragment was created by digestion with papain
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Other Species
- Shipping Conditions:
- Blue Ice
- Specificity:
- 4F11E12 recognises a highly conserved conformational epitope on the surface of the D1 domain in both native and recombinant SAG1, located within the N-terminal domain; the binding site does not overlap with the proposed ligand-binding pocket or homodimerization site. The eptiope is an immunodominant area and includes residues from 2 long loops located at one exteremity. SAG1 is a GPI-anchored cell
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00763-10.0-BT
