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Antibodies
Product Sizes
1 mg
Was £4616.00 £4385.00
AB00761-10-6-BS-1MG
About this Product
SKU:
AB00761-10-6-BS
Additional Names:
latent membrane protein 1; LMP1; LMP-1; p63; protein p63; protein p25
Application:
Block/Inhibit/Neutralise, ELISA, Immunofluorescence, Immunoprecipitation
Buffer:
PBS
translate.label.attr.clone:
H3
Clonality:
Recombinant Monoclonal
Extra Details:
This reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Human
Immunogen:
H3 was selected by its affinity for GST-LMP1 from a human phage display library after 4 rounds of panning.
Purification:
Purified
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Specificity:
H3 scFv is specific to the LMP1 C terminal region where it binds to CTAR-1 (GST-LMP1[187-242]). LMP1 is expessed constitutively in many EBV-associated tumours and this protein can cause B lymphocyte and rodent fibroblast transformation, cell apoptosis inhibition by up-regulation of anti-apoptotic proteins, cell surface marker and DNA methyltransferase activty up-regulation, and cell adhesion molec
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies