Anti-CD40 [A54 scFv]
Product Sizes
1 mg
£4616.00
AB00743-10-6-BS-1MG
About this Product
- SKU:
- AB00743-10-6-BS
- Additional Names:
- TNFRSF5; A54; Tumor necrosis factor receptor superfamily member 5; B cell surface antigen CD40; B-cell cell surface antigen CD40; B-cell surface antigen CD40; B cell surface antigen CD40; antigen CD40; CD40 antigen; Bp50; Bp-50; CD40L receptor CDw40
- Application:
- Activate/Stimulate, Block/Inhibit/Neutralise, ELISA
- Buffer:
- PBS
- translate.label.attr.clone:
- A54 scFv
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- A54 human anti-CD40 scFv was selected from the n-CoDeR phage display library after 4 rounds of selections using biotinylated CD40-FcG Gamma fusion protein as bait and subsequent capture of bound phages on streptavidin-caoted magnetic beads.
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- A54 binds specifically to the D1 domain of CD40 (and can only bind to the intact, i.e., non-truncated version of CD40, and when an AD2 peptide tag has not been added) and can recognise CD40 on a B cell line (BJAB). The scFv version of this antibody binds CD40 (immobilized by amine coupling) with a KD of 40nM. CD40 is a glycoprotein of the TNFR superfamily and is expressed on all mature B cells, de
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00743-10.6-BS
