Anti-DR5 [PRO95780 (Drozitumab)]
Product Sizes
500 ug
AB00740-21-0-BT-500UG
About this Product
- SKU:
- AB00740-21-0-BT
- Additional Names:
- CD262; death receptor 5; TRAIL receptor 2; TRAILR2; tumor necrosis factor receptor superfamily member 10B; TNFRSF10B; apomab
- Application:
- Activate/Stimulate, ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- PRO95780 (Drozitumab)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- The variable domains of this antibody were derived as scFv from a human antibody phage display library, with biotinylated DR5-Fc used to capture DR5-specific phage. The scFv obtained were subsequently reformatted into full-length antibodies.
- Isotype:
- IgM
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for human death receptor 5, a proapoptotic receptor widely expressed in adult and fetal tissues, with notably high expression on tumour cells. Activation of DR5 triggers apoptosis in various types of cancer cells, without affecting most normal cell types.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00740-21.0-BT
