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Antibodies

Anti-IL-6 receptor [rhPM-1 (Tocilizumab)]

Product Sizes
200 ug
Was £463.00 £440.00
AB00737-10-0-200UG
About this Product
SKU:
AB00737-10-0
Additional Names:
IL6R; IL-6R; CD126; MRA; atlizumab; TCZ; Interleukin-6 receptor subunit alpha; IL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA; IL-6R 1; Membrane glycoprotein 80; gp80; PM1; PM-1
Application:
Block/Inhibit/Neutralise, ELISA
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
rhPM-1 (Tocilizumab)
Clonality:
Recombinant Monoclonal
Extra Details:
NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original antibody was generated by CDR grafting of mouse PM-1 antibody onto human REI and NEW framework regions to create rhPM-1.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
Tocilizumab binds specifically to both the membrane bound and soluble forms of human IL-6R. The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies