Anti-CD80 [IDEC-114 (Galiximab)]

Product Sizes

1 mg

AB00736-10-0-BT-1MG

About this Product

SKU:: AB00736-10-0-BT
Additional Names:: B7-1; T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7
Application:: Block/Inhibit/Neutralise, ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:: PBS
translate.label.attr.clone:: IDEC-114 (Galiximab)
Clonality:: Recombinant Monoclonal
Formulation:: PBS only.
Host:: Human
Immunogen:: Galiximab was prepared by immunizing cynomolgus monkeys with recombinant CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and subsequently transfected into the Dg44 CHO cell line (Hariharan K, 2013)
Isotype:: IgG1
Purification:: Purified
Reactivities:: Human
Shipping Conditions:: Blue Ice
Specificity:: Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to CD80. CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells
Storage Conditions:: 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:: Absolute Antibody
Type:: Antibody: Recombinant Antibodies

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