Anti-ADAMts13 [1-420 scFv]
Product Sizes
1 mg
£1962.00
AB00735-2-3-BT-1MG
About this Product
- SKU:
- AB00735-2-3-BT
- Additional Names:
- vWF-CP; ADAM-TS13; ADAMTS-13; C9orf8; VWFCP; ADAM metallopeptidase with thrombospondin type 1 motif 13
- Application:
- Block/Inhibit/Neutralise
- Buffer:
- PBS
- translate.label.attr.clone:
- 1-420 scFv
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This full-length, chimeric mouse antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- 1-420 scFv was generated from a phage display library derived from human TTP patients expressing autoantibodies against ADAMTS13.
- Isotype:
- IgG2a
- Purification:
- Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- Binds to the ADAMTS13 spacer domain. 1-420 binds to the same ADAMTS13 spacer domain loop segments that are required for binding of ADAMTS13 to VWF. ADAMTS13 is a zinc-containing metalloprotease which is secreted in blood where it is able to cleave VWF, a protein involved in blood clotting, to decrease the protein's activity.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00735-2.3-BT
