Anti-CD22 [hL22 (Epratuzumab)]
Product Sizes
200 ug
AB00728-26-0-200UG
About this Product
- SKU:
- AB00728-26-0
- Additional Names:
- Leu14; B-cell receptor CD22; B-lymphocyte cell adhesion molecule; BL-CAM; Sialic acid-binding Ig-like lectin 2; Siglec-2; T-cell surface antigen Leu-14
- Application:
- Block/Inhibit/Neutralise, Flow Cytometry, Immunoprecipitation
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- hL22 (Epratuzumab)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rhesus macaque antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Monkey
- Immunogen:
- This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5-10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010).
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for the 3rd Ig-like domain of human CD22 (epitope B), a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells.
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00728-26.0
