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Antibodies

Anti-CD22 [hL22 (Epratuzumab)]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB00728-10-0-BT-1MG
About this Product
SKU:
AB00728-10-0-BT
Additional Names:
Leu14; B-cell receptor CD22; B-lymphocyte cell adhesion molecule; BL-CAM; Sialic acid-binding Ig-like lectin 2; Siglec-2; T-cell surface antigen Leu-14
Application:
Block/Inhibit/Neutralise, Flow Cytometry, Immunoprecipitation
Buffer:
PBS
translate.label.attr.clone:
hL22 (Epratuzumab)
Clonality:
Recombinant Monoclonal
Formulation:
PBS only.
Host:
Human
Immunogen:
This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5-10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010).
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human, Non-human Primate
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for the 3rd Ig-like domain of human CD22 (epitope B), a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells.
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies