Anti-Integrin beta-7 [FIB27]
Product Sizes
1 mg
AB00627-10-3-BT-1MG
About this Product
- SKU:
- AB00627-10-3-BT
- Additional Names:
- FIB-27; FIB 27; Fib-27; Fib27; Fib 27; fib27; fib-27; fib 27; Integrin b7; integrin b-7; ITGB7; Gut homing receptor beta subunit
- Application:
- Block/Inhibit/Neutralise, Flow Cytometry, Immunoprecipitation
- Buffer:
- PBS
- translate.label.attr.clone:
- FIB27
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- FIB27 was prepared by immunizing rats with TK1 cells.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- FIB27 binds specifically to both human and mouse integrin beta-7 at epitope region Dl on which is involved in all a4b7-mediated adhesion events. Does not compete with DAKT32 for binding. FIB27 blocks LS722-induced TK1 cell aggregation (mAb LS722 is an activating anti-a4B7 antibody and induces aggregation via an a4B7-dependent pathway). Integrin beta-7 is one subunit is a heterodimer which makes up
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00627-10.3-BT
