Anti-CD105 [MJ7/18]
Product Sizes
1 mg
AB00623-2-3-BT-1MG
About this Product
- SKU:
- AB00623-2-3-BT
- Additional Names:
- Endoglin; Cell surface MJ7/18 antigen
- Application:
- Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- MJ7/18
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- MJ7/18 was prepared by immunizing rats with inflamed mouse skin tissue. The antibody was selected immunohistologically for reactivity with endothelial cells.
- Isotype:
- IgG2a
- Purification:
- Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- MJ7/18 binds specifically to mouse CD105. CD105 is a homodimer expressed by vascular endothelial cells. CD105 functions in adhesion and embryonic angiogenesis. CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling casca
- Storage Conditions:
- 2-8[o]C
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00623-2.3-BT
