Anti-CD48 [OX-45]
Product Sizes
1 mg
AB00571-8-4-BT-1MG
About this Product
- SKU:
- AB00571-8-4-BT
- Additional Names:
- BCM1; BCM1 surface antigen; BLAST1; BLAST-1; HM48-1; MRC OX-45 surface antigen; MRC OX45 surface antigen; OX45 surface antigen; OX-45 surface antigen; SLAM family member 2; SLAMF2; sgp60; sgp-60; signalling lymphocytic activation molecule 2 OX45; MRC OX-4
- Application:
- Block/Inhibit/Neutralise, Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- OX-45
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Rat
- Immunogen:
- OX-45 was prepared by immunizing BALB/c mice with rat T blasts prepared by stimulating purified T helper (TH) cells with allogeneic irradiated rat spleen cells.
- Isotype:
- IgG2b
- Purification:
- Purified
- Reactivities:
- Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- OX-45 binds specifically to CD48 on rat thymocytes, T and B cells and endothelium but not LFA.3. Directly competes with CD46 for binding the target epitope. CD48 is a CD2 ligand and is expressed on the surface of all hematopoietic cells and endothelium. May be involved in the facilitation of interactions between activated lymphocytes. Likely to be involved in T cell activation.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab00571-8.4-BT
