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Antibodies

Anti-CD48 [OX-45]

Product Sizes
200 ug
AB00571-8-1-200UG
About this Product
SKU:
AB00571-8-1
Additional Names:
BCM1; BCM1 surface antigen; BLAST1; BLAST-1; HM48-1; MRC OX-45 surface antigen; MRC OX45 surface antigen; OX45 surface antigen; OX-45 surface antigen; SLAM family member 2; SLAMF2; sgp60; sgp-60; signalling lymphocytic activation molecule 2 OX45; MRC OX-4
Application:
Block/Inhibit/Neutralise, Flow Cytometry
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
OX-45
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Rat
Immunogen:
OX-45 was prepared by immunizing BALB/c mice with rat T blasts prepared by stimulating purified T helper (TH) cells with allogeneic irradiated rat spleen cells.
Isotype:
IgG2b
Purification:
Purified
Reactivities:
Rat
Shipping Conditions:
Blue Ice
Specificity:
OX-45 binds specifically to CD48 on rat thymocytes, T and B cells and endothelium but not LFA.3. Directly competes with CD46 for binding the target epitope. CD48 is a CD2 ligand and is expressed on the surface of all hematopoietic cells and endothelium. May be involved in the facilitation of interactions between activated lymphocytes. Likely to be involved in T cell activation.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies